A Novel Multi-Phosphonate Surface Treatment of Titanium Dental Implants: A Study in Sheep
Identifieur interne : 001D70 ( Main/Exploration ); précédent : 001D69; suivant : 001D71A Novel Multi-Phosphonate Surface Treatment of Titanium Dental Implants: A Study in Sheep
Auteurs : Marcella Von Salis-Soglio ; Stefan Stübinger [Suisse] ; Michéle Sidler [Suisse] ; Karina Klein ; Stephen J. Ferguson ; K Thi K Mpf ; Katalin Zlinszky ; Sabrina Buchini ; Richard Curno ; Péter Péchy ; Bjorn-Owe Aronsson ; Brigitte Von RechenbergSource :
- Journal of Functional Biomaterials [ 2079-4983 ] ; 2014.
Abstract
The aim of the present study was to evaluate a new multi-phosphonate surface treatment (SurfLink®) in an unloaded sheep model. Treated implants were compared to control implants in terms of bone to implant contact (BIC), bone formation, and biomechanical stability. The study used two types of implants (rough or machined surface finish) each with either the multi-phosphonate Wet or Dry treatment or no treatment (control) for a total of six groups. Animals were sacrificed after 2, 8, and 52 weeks. No adverse events were observed at any time point. At two weeks, removal torque showed significantly higher values for the multi-phosphonate treated rough surface (+32% and +29%, Dry and Wet, respectively) compared to rough control. At 52 weeks, a significantly higher removal torque was observed for the multi-phosphonate treated machined surfaces (+37% and 23%, Dry and Wet, respectively). The multi-phosphonate treated groups showed a positive tendency for higher BIC with time and increased new-old bone ratio at eight weeks. SEM images revealed greater amounts of organic materials on the multi-phosphonate treated compared to control implants, with the bone fracture (from the torque test) appearing within the bone rather than at the bone to implant interface as it occurred for control implants.
Url:
DOI: 10.3390/jfb5030135
PubMed: 25215424
PubMed Central: 4192609
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 003148
- to stream Pmc, to step Curation: 003148
- to stream Pmc, to step Checkpoint: 001680
- to stream Ncbi, to step Merge: 005474
- to stream Ncbi, to step Curation: 005474
- to stream Ncbi, to step Checkpoint: 005474
- to stream Main, to step Merge: 001D77
- to stream Main, to step Curation: 001D70
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Novel Multi-Phosphonate Surface Treatment of Titanium Dental Implants: A Study in Sheep</title><author><name sortKey="Von Salis Soglio, Marcella" sort="Von Salis Soglio, Marcella" uniqKey="Von Salis Soglio M" first="Marcella" last="Von Salis-Soglio">Marcella Von Salis-Soglio</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Stubinger, Stefan" sort="Stubinger, Stefan" uniqKey="Stubinger S" first="Stefan" last="Stübinger">Stefan Stübinger</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation><affiliation wicri:level="4"><nlm:aff id="af2-jfb-05-00135">Center of Applied Biotechnology and Molecular Medicine (CABMM), Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 190, Zürich 8057, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Center of Applied Biotechnology and Molecular Medicine (CABMM), Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 190, Zürich 8057</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region><settlement type="city">Zurich</settlement></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Sidler, Michele" sort="Sidler, Michele" uniqKey="Sidler M" first="Michéle" last="Sidler">Michéle Sidler</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af3-jfb-05-00135">Veterinary Anaesthesia Services Int (VAS), Zürcherstrasse 39, Winterthur 8400, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Veterinary Anaesthesia Services Int (VAS), Zürcherstrasse 39, Winterthur 8400</wicri:regionArea><wicri:noRegion>Winterthur 8400</wicri:noRegion></affiliation></author><author><name sortKey="Klein, Karina" sort="Klein, Karina" uniqKey="Klein K" first="Karina" last="Klein">Karina Klein</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Ferguson, Stephen J" sort="Ferguson, Stephen J" uniqKey="Ferguson S" first="Stephen J." last="Ferguson">Stephen J. Ferguson</name><affiliation><nlm:aff id="af4-jfb-05-00135">Institute for Biomechanics, ETH Zürich, Vladimir-Prelog-Weg 1-5/10, Zürich 8093, Switzerland; E-Mail:<email>sferguson@ethz.ch</email></nlm:aff></affiliation></author><author><name sortKey="K Mpf, K Thi" sort="K Mpf, K Thi" uniqKey="K Mpf K" first="K Thi" last="K Mpf">K Thi K Mpf</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Zlinszky, Katalin" sort="Zlinszky, Katalin" uniqKey="Zlinszky K" first="Katalin" last="Zlinszky">Katalin Zlinszky</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Buchini, Sabrina" sort="Buchini, Sabrina" uniqKey="Buchini S" first="Sabrina" last="Buchini">Sabrina Buchini</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Curno, Richard" sort="Curno, Richard" uniqKey="Curno R" first="Richard" last="Curno">Richard Curno</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Pechy, Peter" sort="Pechy, Peter" uniqKey="Pechy P" first="Péter" last="Péchy">Péter Péchy</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Aronsson, Bjorn Owe" sort="Aronsson, Bjorn Owe" uniqKey="Aronsson B" first="Bjorn-Owe" last="Aronsson">Bjorn-Owe Aronsson</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Von Rechenberg, Brigitte" sort="Von Rechenberg, Brigitte" uniqKey="Von Rechenberg B" first="Brigitte" last="Von Rechenberg">Brigitte Von Rechenberg</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25215424</idno><idno type="pmc">4192609</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192609</idno><idno type="RBID">PMC:4192609</idno><idno type="doi">10.3390/jfb5030135</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">003148</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003148</idno><idno type="wicri:Area/Pmc/Curation">003148</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003148</idno><idno type="wicri:Area/Pmc/Checkpoint">001680</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001680</idno><idno type="wicri:Area/Ncbi/Merge">005474</idno><idno type="wicri:Area/Ncbi/Curation">005474</idno><idno type="wicri:Area/Ncbi/Checkpoint">005474</idno><idno type="wicri:Area/Main/Merge">001D77</idno><idno type="wicri:Area/Main/Curation">001D70</idno><idno type="wicri:Area/Main/Exploration">001D70</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Novel Multi-Phosphonate Surface Treatment of Titanium Dental Implants: A Study in Sheep</title><author><name sortKey="Von Salis Soglio, Marcella" sort="Von Salis Soglio, Marcella" uniqKey="Von Salis Soglio M" first="Marcella" last="Von Salis-Soglio">Marcella Von Salis-Soglio</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Stubinger, Stefan" sort="Stubinger, Stefan" uniqKey="Stubinger S" first="Stefan" last="Stübinger">Stefan Stübinger</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation><affiliation wicri:level="4"><nlm:aff id="af2-jfb-05-00135">Center of Applied Biotechnology and Molecular Medicine (CABMM), Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 190, Zürich 8057, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Center of Applied Biotechnology and Molecular Medicine (CABMM), Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 190, Zürich 8057</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region><settlement type="city">Zurich</settlement></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Sidler, Michele" sort="Sidler, Michele" uniqKey="Sidler M" first="Michéle" last="Sidler">Michéle Sidler</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af3-jfb-05-00135">Veterinary Anaesthesia Services Int (VAS), Zürcherstrasse 39, Winterthur 8400, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Veterinary Anaesthesia Services Int (VAS), Zürcherstrasse 39, Winterthur 8400</wicri:regionArea><wicri:noRegion>Winterthur 8400</wicri:noRegion></affiliation></author><author><name sortKey="Klein, Karina" sort="Klein, Karina" uniqKey="Klein K" first="Karina" last="Klein">Karina Klein</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Ferguson, Stephen J" sort="Ferguson, Stephen J" uniqKey="Ferguson S" first="Stephen J." last="Ferguson">Stephen J. Ferguson</name><affiliation><nlm:aff id="af4-jfb-05-00135">Institute for Biomechanics, ETH Zürich, Vladimir-Prelog-Weg 1-5/10, Zürich 8093, Switzerland; E-Mail:<email>sferguson@ethz.ch</email></nlm:aff></affiliation></author><author><name sortKey="K Mpf, K Thi" sort="K Mpf, K Thi" uniqKey="K Mpf K" first="K Thi" last="K Mpf">K Thi K Mpf</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Zlinszky, Katalin" sort="Zlinszky, Katalin" uniqKey="Zlinszky K" first="Katalin" last="Zlinszky">Katalin Zlinszky</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author><author><name sortKey="Buchini, Sabrina" sort="Buchini, Sabrina" uniqKey="Buchini S" first="Sabrina" last="Buchini">Sabrina Buchini</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Curno, Richard" sort="Curno, Richard" uniqKey="Curno R" first="Richard" last="Curno">Richard Curno</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Pechy, Peter" sort="Pechy, Peter" uniqKey="Pechy P" first="Péter" last="Péchy">Péter Péchy</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Aronsson, Bjorn Owe" sort="Aronsson, Bjorn Owe" uniqKey="Aronsson B" first="Bjorn-Owe" last="Aronsson">Bjorn-Owe Aronsson</name><affiliation><nlm:aff id="af5-jfb-05-00135">Nano Bridging Molecules SA, Rte Cité Ouest 2, Gland 1196, Switzerland; E-Mails:<email>sabrina.buchini@nbmolecules.com</email> (S.B.);<email>richard.curno@nbmolecules.com</email> (R.C.);<email>peter.pechy@nbmolecules.com</email> (P.P.);<email>bjorn-owe.aronsson@nbmolecules.com</email> (B.-O.A.)</nlm:aff></affiliation></author><author><name sortKey="Von Rechenberg, Brigitte" sort="Von Rechenberg, Brigitte" uniqKey="Von Rechenberg B" first="Brigitte" last="Von Rechenberg">Brigitte Von Rechenberg</name><affiliation><nlm:aff id="af1-jfb-05-00135">Musculoskeletal Research Unit, Equine Hospital, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zürich 8057, Switzerland; E-Mails:<email>msalis@ethz.ch</email> (M.S.-S.);<email>stefan.stuebinger@cabmm.uzh.ch</email> (S.S.);<email>msidler@vetclinics.uzh.ch</email> (M.S.);<email>kklein@vetclinics.uzh.ch</email> (K.Kl.);<email>kkaempf@vetclinics.uzh.ch</email> (K.Kä.);<email>zlin@vetpath.uzh.ch</email> (K.Z.)</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Functional Biomaterials</title><idno type="eISSN">2079-4983</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The aim of the present study was to evaluate a new multi-phosphonate surface treatment (SurfLink<sup>®</sup>) in an unloaded sheep model. Treated implants were compared to control implants in terms of bone to implant contact (BIC), bone formation, and biomechanical stability. The study used two types of implants (rough or machined surface finish) each with either the multi-phosphonate Wet or Dry treatment or no treatment (control) for a total of six groups. Animals were sacrificed after 2, 8, and 52 weeks. No adverse events were observed at any time point. At two weeks, removal torque showed significantly higher values for the multi-phosphonate treated rough surface (+32% and +29%, Dry and Wet, respectively) compared to rough control. At 52 weeks, a significantly higher removal torque was observed for the multi-phosphonate treated machined surfaces (+37% and 23%, Dry and Wet, respectively). The multi-phosphonate treated groups showed a positive tendency for higher BIC with time and increased new-old bone ratio at eight weeks. SEM images revealed greater amounts of organic materials on the multi-phosphonate treated compared to control implants, with the bone fracture (from the torque test) appearing within the bone rather than at the bone to implant interface as it occurred for control implants.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Sennerby, L" uniqKey="Sennerby L">L. Sennerby</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ekelund, J A" uniqKey="Ekelund J">J.-A. Ekelund</name></author><author><name sortKey="Lindquist, L W" uniqKey="Lindquist L">L.W. Lindquist</name></author><author><name sortKey="Carlsson, G E" uniqKey="Carlsson G">G.E. Carlsson</name></author><author><name sortKey="Jemt, T" uniqKey="Jemt T">T. Jemt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adell, R" uniqKey="Adell R">R. Adell</name></author><author><name sortKey="Lekholm, U" uniqKey="Lekholm U">U. Lekholm</name></author><author><name sortKey="Rockler, B" uniqKey="Rockler B">B. Rockler</name></author><author><name sortKey="Br Nemark, P I" uniqKey="Br Nemark P">P.I. Brånemark</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T. Albrektsson</name></author><author><name sortKey="Dahl, E" uniqKey="Dahl E">E. Dahl</name></author><author><name sortKey="Enbom, L" uniqKey="Enbom L">L. Enbom</name></author><author><name sortKey="Engevall, S" uniqKey="Engevall S">S. Engevall</name></author><author><name sortKey="Engquist, B" uniqKey="Engquist B">B. Engquist</name></author><author><name sortKey="Eriksson, A R" uniqKey="Eriksson A">A.R. Eriksson</name></author><author><name sortKey="Feldmann, G" uniqKey="Feldmann G">G. Feldmann</name></author><author><name sortKey="Freiberg, N" uniqKey="Freiberg N">N. Freiberg</name></author><author><name sortKey="Glantz, P O" uniqKey="Glantz P">P.O. Glantz</name></author><author><name sortKey="Kjellman, O" uniqKey="Kjellman O">O. Kjellman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brunette, D" uniqKey="Brunette D">D. Brunette</name></author><author><name sortKey="Tengvall, P" uniqKey="Tengvall P">P. Tengvall</name></author><author><name sortKey="Textor, M" uniqKey="Textor M">M. Textor</name></author><author><name sortKey="Thomsen, P" uniqKey="Thomsen P">P. Thomsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Akagawa, Y" uniqKey="Akagawa Y">Y. Akagawa</name></author><author><name sortKey="Abe, Y" uniqKey="Abe Y">Y. Abe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Esposito, M" uniqKey="Esposito M">M. Esposito</name></author><author><name sortKey="Murray Curtis, L" uniqKey="Murray Curtis L">L. Murray-Curtis</name></author><author><name sortKey="Grusovin, M G" uniqKey="Grusovin M">M.G. Grusovin</name></author><author><name sortKey="Coulthard, P" uniqKey="Coulthard P">P. Coulthard</name></author><author><name sortKey="Worthington, H V" uniqKey="Worthington H">H.V. Worthington</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Junker, R" uniqKey="Junker R">R. Junker</name></author><author><name sortKey="Dimakis, A" uniqKey="Dimakis A">A. Dimakis</name></author><author><name sortKey="Thoneick, M" uniqKey="Thoneick M">M. Thoneick</name></author><author><name sortKey="Jansen, J A" uniqKey="Jansen J">J.A. Jansen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mendonca, G" uniqKey="Mendonca G">G. Mendonça</name></author><author><name sortKey="Mendonca, D B S" uniqKey="Mendonca D">D.B.S. Mendonça</name></author><author><name sortKey="Aragao, F J L" uniqKey="Aragao F">F.J.L. Aragão</name></author><author><name sortKey="Cooper, L F" uniqKey="Cooper L">L.F. Cooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Le Guehennec, L" uniqKey="Le Guehennec L">L. Le Guéhennec</name></author><author><name sortKey="Soueidan, A" uniqKey="Soueidan A">A. Soueidan</name></author><author><name sortKey="Layrolle, P" uniqKey="Layrolle P">P. Layrolle</name></author><author><name sortKey="Amouriq, Y" uniqKey="Amouriq Y">Y. Amouriq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Creugers, N H" uniqKey="Creugers N">N.H. Creugers</name></author><author><name sortKey="Kreulen, C M" uniqKey="Kreulen C">C.M. Kreulen</name></author><author><name sortKey="Snoek, P A" uniqKey="Snoek P">P.A. Snoek</name></author><author><name sortKey="De Kanter, R J" uniqKey="De Kanter R">R.J. de Kanter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bartlett, D" uniqKey="Bartlett D">D. Bartlett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Friberg, B" uniqKey="Friberg B">B. Friberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puleo, D A" uniqKey="Puleo D">D.A. Puleo</name></author><author><name sortKey="Thomas, M V" uniqKey="Thomas M">M.V. Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suvan, J" uniqKey="Suvan J">J. Suvan</name></author><author><name sortKey="Petrie, A" uniqKey="Petrie A">A. Petrie</name></author><author><name sortKey="Moles, D R" uniqKey="Moles D">D.R. Moles</name></author><author><name sortKey="Nibali, L" uniqKey="Nibali L">L. Nibali</name></author><author><name sortKey="Patel, K" uniqKey="Patel K">K. Patel</name></author><author><name sortKey="Darbar, U" uniqKey="Darbar U">U. Darbar</name></author><author><name sortKey="Donos, N" uniqKey="Donos N">N. Donos</name></author><author><name sortKey="Tonetti, M" uniqKey="Tonetti M">M. Tonetti</name></author><author><name sortKey="D Iuto, F" uniqKey="D Iuto F">F. D’Aiuto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scully, C" uniqKey="Scully C">C. Scully</name></author><author><name sortKey="Hobkirk, J" uniqKey="Hobkirk J">J. Hobkirk</name></author><author><name sortKey="Dios, P D" uniqKey="Dios P">P.D. Dios</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lekholm, U" uniqKey="Lekholm U">U. Lekholm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cano, J" uniqKey="Cano J">J. Cano</name></author><author><name sortKey="Campo, J" uniqKey="Campo J">J. Campo</name></author><author><name sortKey="Vaquero, J J" uniqKey="Vaquero J">J.J. Vaquero</name></author><author><name sortKey="Martinez Gonzalez, J M" uniqKey="Martinez Gonzalez J">J.M. Martínez González</name></author><author><name sortKey="Bascones, A" uniqKey="Bascones A">A. Bascones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Sabbagh, M" uniqKey="Al Sabbagh M">M. Al-Sabbagh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T. Albrektsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shalabi, M M" uniqKey="Shalabi M">M.M. Shalabi</name></author><author><name sortKey="Gortemaker, A" uniqKey="Gortemaker A">A. Gortemaker</name></author><author><name sortKey="Van Hof, M A" uniqKey="Van Hof M">M.A. Van’t Hof</name></author><author><name sortKey="Jansen, J A" uniqKey="Jansen J">J.A. Jansen</name></author><author><name sortKey="Creugers, N H J" uniqKey="Creugers N">N.H.J. Creugers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cooper, L F" uniqKey="Cooper L">L.F. Cooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T. Albrektsson</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="J Ger, M" uniqKey="J Ger M">M. Jäger</name></author><author><name sortKey="Zilkens, C" uniqKey="Zilkens C">C. Zilkens</name></author><author><name sortKey="Zanger, K" uniqKey="Zanger K">K. Zanger</name></author><author><name sortKey="Krauspe, R" uniqKey="Krauspe R">R. Krauspe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maekawa, K" uniqKey="Maekawa K">K. Maekawa</name></author><author><name sortKey="Yoshida, Y" uniqKey="Yoshida Y">Y. Yoshida</name></author><author><name sortKey="Mine, A" uniqKey="Mine A">A. Mine</name></author><author><name sortKey="Fujisawa, T" uniqKey="Fujisawa T">T. Fujisawa</name></author><author><name sortKey="Van Meerbeek, B" uniqKey="Van Meerbeek B">B. Van Meerbeek</name></author><author><name sortKey="Suzuki, K" uniqKey="Suzuki K">K. Suzuki</name></author><author><name sortKey="Kuboki, T" uniqKey="Kuboki T">T. Kuboki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maekawa, K" uniqKey="Maekawa K">K. Maekawa</name></author><author><name sortKey="Shimono, K" uniqKey="Shimono K">K. Shimono</name></author><author><name sortKey="Oshima, M" uniqKey="Oshima M">M. Oshima</name></author><author><name sortKey="Yoshida, Y" uniqKey="Yoshida Y">Y. Yoshida</name></author><author><name sortKey="Van Meerbeek, B" uniqKey="Van Meerbeek B">B. Van Meerbeek</name></author><author><name sortKey="Suzuki, K" uniqKey="Suzuki K">K. Suzuki</name></author><author><name sortKey="Kuboki, T" uniqKey="Kuboki T">T. Kuboki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kawazoe, Y" uniqKey="Kawazoe Y">Y. Kawazoe</name></author><author><name sortKey="Shiba, T" uniqKey="Shiba T">T. Shiba</name></author><author><name sortKey="Nakamura, R" uniqKey="Nakamura R">R. Nakamura</name></author><author><name sortKey="Mizuno, A" uniqKey="Mizuno A">A. Mizuno</name></author><author><name sortKey="Tsutsumi, K" uniqKey="Tsutsumi K">K. Tsutsumi</name></author><author><name sortKey="Uematsu, T" uniqKey="Uematsu T">T. Uematsu</name></author><author><name sortKey="Yamaoka, M" uniqKey="Yamaoka M">M. Yamaoka</name></author><author><name sortKey="Shindoh, M" uniqKey="Shindoh M">M. Shindoh</name></author><author><name sortKey="Kohgo, T" uniqKey="Kohgo T">T. Kohgo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harada, K" uniqKey="Harada K">K. Harada</name></author><author><name sortKey="Itoh, H" uniqKey="Itoh H">H. Itoh</name></author><author><name sortKey="Kawazoe, Y" uniqKey="Kawazoe Y">Y. Kawazoe</name></author><author><name sortKey="Miyazaki, S" uniqKey="Miyazaki S">S. Miyazaki</name></author><author><name sortKey="Doi, K" uniqKey="Doi K">K. Doi</name></author><author><name sortKey="Kubo, T" uniqKey="Kubo T">T. Kubo</name></author><author><name sortKey="Akagawa, Y" uniqKey="Akagawa Y">Y. Akagawa</name></author><author><name sortKey="Shiba, T" uniqKey="Shiba T">T. Shiba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Russell, R G G" uniqKey="Russell R">R.G.G. Russell</name></author><author><name sortKey="Watts, N B" uniqKey="Watts N">N.B. Watts</name></author><author><name sortKey="Ebetino, F H" uniqKey="Ebetino F">F.H. Ebetino</name></author><author><name sortKey="Rogers, M J" uniqKey="Rogers M">M.J. Rogers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gittens, R A" uniqKey="Gittens R">R.A. Gittens</name></author><author><name sortKey="Scheideler, L" uniqKey="Scheideler L">L. Scheideler</name></author><author><name sortKey="Rupp, F" uniqKey="Rupp F">F. Rupp</name></author><author><name sortKey="Hyzy, S L" uniqKey="Hyzy S">S.L. Hyzy</name></author><author><name sortKey="Geis Gerstorfer, J" uniqKey="Geis Gerstorfer J">J. Geis-Gerstorfer</name></author><author><name sortKey="Schwartz, Z" uniqKey="Schwartz Z">Z. Schwartz</name></author><author><name sortKey="Boyan, B D" uniqKey="Boyan B">B.D. Boyan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shannon, F J" uniqKey="Shannon F">F.J. Shannon</name></author><author><name sortKey="Cottrell, J M" uniqKey="Cottrell J">J.M. Cottrell</name></author><author><name sortKey="Deng, X H" uniqKey="Deng X">X.-H. Deng</name></author><author><name sortKey="Crowder, K N" uniqKey="Crowder K">K.N. Crowder</name></author><author><name sortKey="Doty, S B" uniqKey="Doty S">S.B. Doty</name></author><author><name sortKey="Avaltroni, M J" uniqKey="Avaltroni M">M.J. Avaltroni</name></author><author><name sortKey="Warren, R F" uniqKey="Warren R">R.F. Warren</name></author><author><name sortKey="Wright, T M" uniqKey="Wright T">T.M. Wright</name></author><author><name sortKey="Schwartz, J" uniqKey="Schwartz J">J. Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Auernheimer, J" uniqKey="Auernheimer J">J. Auernheimer</name></author><author><name sortKey="Zukowski, D" uniqKey="Zukowski D">D. Zukowski</name></author><author><name sortKey="Dahmen, C" uniqKey="Dahmen C">C. Dahmen</name></author><author><name sortKey="Kantlehner, M" uniqKey="Kantlehner M">M. Kantlehner</name></author><author><name sortKey="Enderle, A" uniqKey="Enderle A">A. Enderle</name></author><author><name sortKey="Goodman, S L" uniqKey="Goodman S">S.L. Goodman</name></author><author><name sortKey="Kessler, H" uniqKey="Kessler H">H. Kessler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heijink, A" uniqKey="Heijink A">A. Heijink</name></author><author><name sortKey="Schwartz, J" uniqKey="Schwartz J">J. Schwartz</name></author><author><name sortKey="Zobitz, M E" uniqKey="Zobitz M">M.E. Zobitz</name></author><author><name sortKey="Nicole Crowder, K" uniqKey="Nicole Crowder K">K. Nicole Crowder</name></author><author><name sortKey="Lutz, G E" uniqKey="Lutz G">G.E. Lutz</name></author><author><name sortKey="Sibonga, J D" uniqKey="Sibonga J">J.D. Sibonga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Viornery, C" uniqKey="Viornery C">C. Viornery</name></author><author><name sortKey="Chevolot, Y" uniqKey="Chevolot Y">Y. Chevolot</name></author><author><name sortKey="Leonard, D" uniqKey="Leonard D">D. Léonard</name></author><author><name sortKey="Aronsson, B O" uniqKey="Aronsson B">B.-O. Aronsson</name></author><author><name sortKey="Pechy, P" uniqKey="Pechy P">P. Péchy</name></author><author><name sortKey="Mathieu, H J" uniqKey="Mathieu H">H.J. Mathieu</name></author><author><name sortKey="Descouts, P" uniqKey="Descouts P">P. Descouts</name></author><author><name sortKey="Gr Tzel, M" uniqKey="Gr Tzel M">M. Grätzel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Esposito, M" uniqKey="Esposito M">M. Esposito</name></author><author><name sortKey="Grusovin, M G" uniqKey="Grusovin M">M.G. Grusovin</name></author><author><name sortKey="Achille, H" uniqKey="Achille H">H. Achille</name></author><author><name sortKey="Coulthard, P" uniqKey="Coulthard P">P. Coulthard</name></author><author><name sortKey="Worthington, H V" uniqKey="Worthington H">H.V. Worthington</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Viornery, C" uniqKey="Viornery C">C. Viornery</name></author><author><name sortKey="Guenther, H L" uniqKey="Guenther H">H.L. Guenther</name></author><author><name sortKey="Aronsson, B O" uniqKey="Aronsson B">B.-O. Aronsson</name></author><author><name sortKey="Pechy, P" uniqKey="Pechy P">P. Péchy</name></author><author><name sortKey="Descouts, P" uniqKey="Descouts P">P. Descouts</name></author><author><name sortKey="Gr Tzel, M" uniqKey="Gr Tzel M">M. Grätzel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Terheyden, H" uniqKey="Terheyden H">H. Terheyden</name></author><author><name sortKey="Lang, N P" uniqKey="Lang N">N.P. Lang</name></author><author><name sortKey="Bierbaum, S" uniqKey="Bierbaum S">S. Bierbaum</name></author><author><name sortKey="Stadlinger, B" uniqKey="Stadlinger B">B. Stadlinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dayer, R" uniqKey="Dayer R">R. Dayer</name></author><author><name sortKey="Rizzoli, R" uniqKey="Rizzoli R">R. Rizzoli</name></author><author><name sortKey="Pechy, P" uniqKey="Pechy P">P. Péchy</name></author><author><name sortKey="Vig, T" uniqKey="Vig T">T. Vig</name></author><author><name sortKey="Aronsson, B O" uniqKey="Aronsson B">B.-O. Aronsson</name></author><author><name sortKey="Descouts, P" uniqKey="Descouts P">P. Descouts</name></author><author><name sortKey="Ammann, P" uniqKey="Ammann P">P. Ammann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Esposito, M" uniqKey="Esposito M">M. Esposito</name></author><author><name sortKey="Dojcinovic, I" uniqKey="Dojcinovic I">I. Dojcinovic</name></author><author><name sortKey="Germon, L" uniqKey="Germon L">L. Germon</name></author><author><name sortKey="Levy, N" uniqKey="Levy N">N. Lévy</name></author><author><name sortKey="Curno, R" uniqKey="Curno R">R. Curno</name></author><author><name sortKey="Buchini, S" uniqKey="Buchini S">S. Buchini</name></author><author><name sortKey="Pechy, P" uniqKey="Pechy P">P. Péchy</name></author><author><name sortKey="Aronsson, B O" uniqKey="Aronsson B">B.-O. Aronsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Langhoff, J D" uniqKey="Langhoff J">J.D. Langhoff</name></author><author><name sortKey="Voelter, K" uniqKey="Voelter K">K. Voelter</name></author><author><name sortKey="Scharnweber, D" uniqKey="Scharnweber D">D. Scharnweber</name></author><author><name sortKey="Schnabelrauch, M" uniqKey="Schnabelrauch M">M. Schnabelrauch</name></author><author><name sortKey="Schlottig, F" uniqKey="Schlottig F">F. Schlottig</name></author><author><name sortKey="Hefti, T" uniqKey="Hefti T">T. Hefti</name></author><author><name sortKey="Kalchofner, K" uniqKey="Kalchofner K">K. Kalchofner</name></author><author><name sortKey="Nuss, K" uniqKey="Nuss K">K. Nuss</name></author><author><name sortKey="Von Rechenberg, B" uniqKey="Von Rechenberg B">B. von Rechenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martini, L" uniqKey="Martini L">L. Martini</name></author><author><name sortKey="Fini, M" uniqKey="Fini M">M. Fini</name></author><author><name sortKey="Giavaresi, G" uniqKey="Giavaresi G">G. Giavaresi</name></author><author><name sortKey="Giardino, R" uniqKey="Giardino R">R. Giardino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Apelt, D" uniqKey="Apelt D">D. Apelt</name></author><author><name sortKey="Theiss, F" uniqKey="Theiss F">F. Theiss</name></author><author><name sortKey="El Warrak, A O" uniqKey="El Warrak A">A.O. El-Warrak</name></author><author><name sortKey="Zlinszky, K" uniqKey="Zlinszky K">K. Zlinszky</name></author><author><name sortKey="Bettschart Wolfisberger, R" uniqKey="Bettschart Wolfisberger R">R. Bettschart-Wolfisberger</name></author><author><name sortKey="Bohner, M" uniqKey="Bohner M">M. Bohner</name></author><author><name sortKey="Matter, S" uniqKey="Matter S">S. Matter</name></author><author><name sortKey="Auer, J A" uniqKey="Auer J">J.A. Auer</name></author><author><name sortKey="Von Rechenberg, B" uniqKey="Von Rechenberg B">B. von Rechenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuttenberger, J J" uniqKey="Kuttenberger J">J.J. Kuttenberger</name></author><author><name sortKey="Waibel, A" uniqKey="Waibel A">A. Waibel</name></author><author><name sortKey="Stubinger, S" uniqKey="Stubinger S">S. Stübinger</name></author><author><name sortKey="Werner, M" uniqKey="Werner M">M. Werner</name></author><author><name sortKey="Klasing, M" uniqKey="Klasing M">M. Klasing</name></author><author><name sortKey="Ivanenko, M" uniqKey="Ivanenko M">M. Ivanenko</name></author><author><name sortKey="Hering, P" uniqKey="Hering P">P. Hering</name></author><author><name sortKey="Von Rechenberg, B" uniqKey="Von Rechenberg B">B. von Rechenberg</name></author><author><name sortKey="Sader, R" uniqKey="Sader R">R. Sader</name></author><author><name sortKey="Zeilhofer, H F" uniqKey="Zeilhofer H">H.-F. Zeilhofer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Newman, E" uniqKey="Newman E">E. Newman</name></author><author><name sortKey="Turner, A S" uniqKey="Turner A">A.S. Turner</name></author><author><name sortKey="Wark, J D" uniqKey="Wark J">J.D. Wark</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kimmel, D B" uniqKey="Kimmel D">D.B. Kimmel</name></author><author><name sortKey="Jee, W S" uniqKey="Jee W">W.S. Jee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Nawas, B" uniqKey="Al Nawas B">B. Al-Nawas</name></author><author><name sortKey="Groetz, K A" uniqKey="Groetz K">K.A. Groetz</name></author><author><name sortKey="Goetz, H" uniqKey="Goetz H">H. Goetz</name></author><author><name sortKey="Duschner, H" uniqKey="Duschner H">H. Duschner</name></author><author><name sortKey="Wagner, W" uniqKey="Wagner W">W. Wagner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morand, M" uniqKey="Morand M">M. Morand</name></author><author><name sortKey="Irinakis, T" uniqKey="Irinakis T">T. Irinakis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abrahamsson, I" uniqKey="Abrahamsson I">I. Abrahamsson</name></author><author><name sortKey="Linder, E" uniqKey="Linder E">E. Linder</name></author><author><name sortKey="Larsson, L" uniqKey="Larsson L">L. Larsson</name></author><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T. Berglundh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wheeler, S L" uniqKey="Wheeler S">S.L. Wheeler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Oirschot, B A J A" uniqKey="Van Oirschot B">B.A.J.A. Van Oirschot</name></author><author><name sortKey="Bronkhorst, E M" uniqKey="Bronkhorst E">E.M. Bronkhorst</name></author><author><name sortKey="Van Den Beucken, J J J P" uniqKey="Van Den Beucken J">J.J.J.P. van den Beucken</name></author><author><name sortKey="Meijer, G J" uniqKey="Meijer G">G.J. Meijer</name></author><author><name sortKey="Jansen, J A" uniqKey="Jansen J">J.A. Jansen</name></author><author><name sortKey="Junker, R" uniqKey="Junker R">R. Junker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albrektsson, T O" uniqKey="Albrektsson T">T.O. Albrektsson</name></author><author><name sortKey="Johansson, C B" uniqKey="Johansson C">C.B. Johansson</name></author><author><name sortKey="Sennerby, L" uniqKey="Sennerby L">L. Sennerby</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gholami, H" uniqKey="Gholami H">H. Gholami</name></author><author><name sortKey="Mericske Stern, R" uniqKey="Mericske Stern R">R. Mericske-Stern</name></author><author><name sortKey="Kessler Liechti, G" uniqKey="Kessler Liechti G">G. Kessler-Liechti</name></author><author><name sortKey="Katsoulis, J" uniqKey="Katsoulis J">J. Katsoulis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Esposito, M" uniqKey="Esposito M">M. Esposito</name></author><author><name sortKey="Hirsch, J M" uniqKey="Hirsch J">J.M. Hirsch</name></author><author><name sortKey="Lekholm, U" uniqKey="Lekholm U">U. Lekholm</name></author><author><name sortKey="Thomsen, P" uniqKey="Thomsen P">P. Thomsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kong, Y M" uniqKey="Kong Y">Y.-M. Kong</name></author><author><name sortKey="Kim, D H" uniqKey="Kim D">D.-H. Kim</name></author><author><name sortKey="Kim, H E" uniqKey="Kim H">H.-E. Kim</name></author><author><name sortKey="Heo, S J" uniqKey="Heo S">S.-J. Heo</name></author><author><name sortKey="Koak, J Y" uniqKey="Koak J">J.-Y. Koak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sabbatini, L" uniqKey="Sabbatini L">L. Sabbatini</name></author><author><name sortKey="Zambonin, P G" uniqKey="Zambonin P">P.G. Zambonin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buser, D" uniqKey="Buser D">D. Buser</name></author><author><name sortKey="Nydegger, T" uniqKey="Nydegger T">T. Nydegger</name></author><author><name sortKey="Oxland, T" uniqKey="Oxland T">T. Oxland</name></author><author><name sortKey="Cochran, D L" uniqKey="Cochran D">D.L. Cochran</name></author><author><name sortKey="Schenk, R K" uniqKey="Schenk R">R.K. Schenk</name></author><author><name sortKey="Hirt, H P" uniqKey="Hirt H">H.P. Hirt</name></author><author><name sortKey="Snetivy, D" uniqKey="Snetivy D">D. Snétivy</name></author><author><name sortKey="Nolte, L P" uniqKey="Nolte L">L.P. Nolte</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferguson, S J" uniqKey="Ferguson S">S.J. Ferguson</name></author><author><name sortKey="Langhoff, J D" uniqKey="Langhoff J">J.D. Langhoff</name></author><author><name sortKey="Voelter, K" uniqKey="Voelter K">K. Voelter</name></author><author><name sortKey="Von Rechenberg, B" uniqKey="Von Rechenberg B">B. von Rechenberg</name></author><author><name sortKey="Scharnweber, D" uniqKey="Scharnweber D">D. Scharnweber</name></author><author><name sortKey="Bierbaum, S" uniqKey="Bierbaum S">S. Bierbaum</name></author><author><name sortKey="Schnabelrauch, M" uniqKey="Schnabelrauch M">M. Schnabelrauch</name></author><author><name sortKey="Kautz, A R" uniqKey="Kautz A">A.R. Kautz</name></author><author><name sortKey="Frauchiger, V M" uniqKey="Frauchiger V">V.M. Frauchiger</name></author><author><name sortKey="Mueller, T L" uniqKey="Mueller T">T.L. Mueller</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Suisse</li></country><region><li>Canton de Zurich</li></region><settlement><li>Zurich</li></settlement><orgName><li>Université de Zurich</li></orgName></list><tree><noCountry><name sortKey="Aronsson, Bjorn Owe" sort="Aronsson, Bjorn Owe" uniqKey="Aronsson B" first="Bjorn-Owe" last="Aronsson">Bjorn-Owe Aronsson</name><name sortKey="Buchini, Sabrina" sort="Buchini, Sabrina" uniqKey="Buchini S" first="Sabrina" last="Buchini">Sabrina Buchini</name><name sortKey="Curno, Richard" sort="Curno, Richard" uniqKey="Curno R" first="Richard" last="Curno">Richard Curno</name><name sortKey="Ferguson, Stephen J" sort="Ferguson, Stephen J" uniqKey="Ferguson S" first="Stephen J." last="Ferguson">Stephen J. Ferguson</name><name sortKey="K Mpf, K Thi" sort="K Mpf, K Thi" uniqKey="K Mpf K" first="K Thi" last="K Mpf">K Thi K Mpf</name><name sortKey="Klein, Karina" sort="Klein, Karina" uniqKey="Klein K" first="Karina" last="Klein">Karina Klein</name><name sortKey="Pechy, Peter" sort="Pechy, Peter" uniqKey="Pechy P" first="Péter" last="Péchy">Péter Péchy</name><name sortKey="Von Rechenberg, Brigitte" sort="Von Rechenberg, Brigitte" uniqKey="Von Rechenberg B" first="Brigitte" last="Von Rechenberg">Brigitte Von Rechenberg</name><name sortKey="Von Salis Soglio, Marcella" sort="Von Salis Soglio, Marcella" uniqKey="Von Salis Soglio M" first="Marcella" last="Von Salis-Soglio">Marcella Von Salis-Soglio</name><name sortKey="Zlinszky, Katalin" sort="Zlinszky, Katalin" uniqKey="Zlinszky K" first="Katalin" last="Zlinszky">Katalin Zlinszky</name></noCountry><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Stubinger, Stefan" sort="Stubinger, Stefan" uniqKey="Stubinger S" first="Stefan" last="Stübinger">Stefan Stübinger</name></region><name sortKey="Sidler, Michele" sort="Sidler, Michele" uniqKey="Sidler M" first="Michéle" last="Sidler">Michéle Sidler</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D70 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001D70 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4192609
|texte= A Novel Multi-Phosphonate Surface Treatment of Titanium Dental Implants: A Study in Sheep
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25215424" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |